Teaching

Jean-Christophe teaches both fundamentals and more advanced concepts in organic chemistry from the Bachelor to the Master level within the Chemistry curriculum at the Department of Chemistry.

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Organic Chemistry I CHIM9265-1 (first year)

This series of lectures sets the most fundamental aspects of organic chemistry within the current societal context and prepares the students for the most advanced applications in organic chemistry.

 • Chapter I: Organic Chemistry: some history and current status
 • Chapter II: Structure and bonding
 • Chapter III: Nomenclature
 • Chapter IV: Stereochemistry
 • Chapter V: Fundamentals of reactivity
 • Chapter VI: Alkanes et cycloalkanes
 • Chapter VII: Alkenes et alkynes
 • Chapter VIII: Introduction to thermal cycloadditions
 • Chapter IX: Aromatic compounds
 • Chapter X: Nucleophilic substitution and elimination reactions
 • Chapter XI: Carbonylated derivatives
 • Chapter XII: Revisions

Organic Chemistry II CHIM9283 (second year)

 

 

 

 

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This series of lectures builds upon the most fundamental aspects of organic chemistry and expands the horizon to other elements than H, C, O. The students will discover within the first part the rich diversity and synthetic utility of nitrogen-, phosphorus-, sulfur-, selenium- and silicon-containing organic derivatives.
The second part of this series of lectures is dedicated to C-based species, including carbanions, carbocations, radicals and carbenes.

 Part 1
•    Chapter I: Recap on the fundamental concepts
•    Chapter II: The organic chemistry of nitrogen-containing compounds
•    Chapter III: Organophosphorus derivatives
•    Chapter IV: Sulfur and Selenium derivatives
•    Chapter V: Organosilanes

 Part 2
•    Chapter I: Carbanions
•    Chapter II: Carbocations
•    Chapter III: Radicals
•    Chapter IV: Introduction to carbenes and carbenoids
•    Chapter V: Revisions

Advanced Organic Chemistry CHIM704 (fourth year)

Organic Chemistry consists in a series of lectures building upon the fundamentals of organic chemistry taught in Organic Chemistry I, II and II (Bachelor). The course starts with a thorough introduction on the concepts of retrosynthetic analysis and the principles of total synthesis. The student is next confronted to a selection of classical total syntheses for the preparation of complex bioactive organic molecules. In addition to total synthesis, this series of lectures also proposes introductory concepts of Green Chemistry and the main challenges for Organic Chemistry in the 21st century. Some additional concepts related to reactivity and selectivity are also presented for the optimization of chemical syntheses and the reduction of their environmental impact. A large diversity of examples and exercises are used to illustrate the theoretical concepts.

Introduction to Continuous Flow Organic Synthesis CHIM9265-1 (fourth/fifth year, optional)

This series of lectures will benefit to students, researchers and professionals in chemistry who are interested in organic chemistry, pharmaceutical, fine chemical, R&D and manufacturing applications. Fundamental principles and technologies used in the continuous manufacturing of small organic molecules, as well as recent examples from the literature will be thoroughly discussed. Attendees will not only receive an extensive state-of-the-art overview, but will also be given a chance to manipulate equipment and design continuous flow synthetic routes.

•    Lecture 1: Definitions and Concepts
•    Lecture 2: Chemical Engineering Principles for Continuous Flow Synthesis
•    Lecture 3: Continuous Flow Organic Synthesis
•    Lecture 4: Miscellaneous Applications
•    Lecture 5: Downstream Operation and In-Line Analysis
•    Lecture 6: Industrial Applications of Continuous Flow Organic Chemistry

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Physical Organic Chemistry CHIM0707-1 (fourth/fifth year, optional)

This course will benefit to students and researchers in chemistry who are interested in getting a more in-depth rationalization of reactivity in organic chemistry. CHIM0707 complements basic notions and fundamental concepts of reactivity and furnishes the appropriate tools for a deeper understanding. The students will also be acquainted with modern methodology for the computation of molecular properties, reaction mechanisms and selectivity.

•    Lecture 1: Thermodynamic and Kinetic Requirements – Summary of Mechanistic Principles
•    Lecture 2: Linear Free Energy Relationships
•    Lecture 3: Stereochemistry
•    Lecture 4: The computation of Relevant Molecular Properties for the Organic chemist
•    Lecture 5: The computation of Reaction Mechanisms and Selectivity

Chemistry and Physico-chemistry of peptide and protein assemblies CHIM0731 (fourth/fifth year, optional)

This series of lectures will benefit to organic chemists and biochemists interested in understanding the synthetic procedures for the preparation of peptides and proteins. It starts with a thorough introduction on the modern concepts and methods for the preparation of peptides and proteins, using extraction from natural sources, recombinant techniques and total synthesis. Then additional lectures will be dedicated to the main approaches used for determining the sequences and the structures of natural peptides.

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